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Turn on memory stick speed up to game. This will speed up the memory stick when ever you are playing a game. This will result in faster loading times.
Clock your CPU to 333/166 for game. This will speed up game play but lower battery life slightly.
If you are running at 6.60 pro-b9 , then under your advanced option in your recovery menu, enable inferno & np9660 iso cache, change your "inferno & np9660 cache size (in mb)" to 23. I'm not sure what this does but i guess because it's a cache, if you increase the size the more space you will have in the cache for whatever it is used for.
In your options menu of nzp, turn off anti-aliasing
Turn on mipmap and set the amount to the max (this will lower the texture quality by a lot)
Max out the maximum fps.
Turn off dynamic lighting.
Turn texture scale down on.
Turn off VSync.